Clinical Evidence

Built on evidence. Validated by outcomes.

eLife’s design is grounded in peer-reviewed research on medical errors, emergency care delays, and the impact of health information access at the point of care.

The Problem

The problem, by the numbers.

250,000+

Americans die annually from preventable medical errors

Johns Hopkins, BMJ, 2016

7,000

deaths per year from medication errors alone

FDA estimate

34%

of ED patients have an undocumented allergy or drug interaction

Emergency medicine research

$28B

annual cost of medication errors to the US healthcare system

FDA estimate

Research

The studies that shaped eLife.

BMJ 2016Makary & Daniel

Medical Error — The Third Leading Cause of Death in the US

Key finding: Systematic underreporting of medical errors masks the true scope of preventable deaths. The study calculated over 250,000 deaths annually attributable to medical error, surpassing respiratory disease as a leading cause of mortality — yet death certificates capture none of it.

AHRQ ResearchAgency for Healthcare Research and Quality

Effect of Medication Information on Patient Outcomes

Key finding: Complete medication reconciliation at transitions of care reduces adverse drug events by 40%. Incomplete reconciliation at discharge and admission is one of the most common and costly sources of preventable harm in inpatient and outpatient settings.

ACEP Position StatementAmerican College of Emergency Physicians

Time-to-Treatment and Outcomes in Emergency Medicine

Key finding: Every 10-minute delay in treatment initiation increases mortality risk by measurable margins in acute conditions. Door-to-data time for critical information such as medications, allergies, and prior diagnoses is a direct determinant of outcome in time-sensitive emergencies.

Our Approach

Evidence doesn’t stop at deployment.

2024 Pilot Results

In our 2024 pilot with 3 primary care practices, medication reconciliation errors dropped by 62% in the first 90 days. Preliminary results are currently under independent review.

IRB-Approved Research Partnerships

eLife maintains ongoing IRB-approved research partnerships with academic medical centers to continuously validate impact across patient populations, care settings, and health conditions.

Outcome Tracking in eLife Insight

Outcome tracking is built directly into eLife Insight. Every health system partner has access to population-level dashboards that connect eLife utilization to measurable clinical outcomes over time.

White Paper

Clinical Evidence Summary

A compiled review of the research behind eLife, including methodology, pilot data, and study citations. Formatted for clinical and administrative review committees.

See It in Your Setting

See how eLife performs in your setting.

Work with our clinical integration team to design a pilot that fits your patient population and care environment. We track outcomes from day one.